If I'm feeling lazy to begin with, I'll usually just use a vibe on my clit and get off that way. Then there's really nothing to clean up.
If I'm not feeling too lazy I might get out some of my dildos and have a party, but then there's more clean up.
Meh, it depends. I have to admit that more than once I've put dirty toys back in the drawer. They gets cleaned before getting used again though.