The way it's supposed to work, theoretically, is that higher-grade 'pure' silicone is more resilient to silicone lube. A product that just contains some silicone (like TPR) will likely react more and break down when in contact with silicone lube. I can see why Vixskin might react more (and why O2 might as well, Jimbo) since the consistency of it is different and somehow closer to the chemical consistency of silicone lube than standard hard silicone.
Easy way to find out- put a dot of silicone lube on the base of the dildo and see what happens. If it does get gummy, you haven't ruined the toy. If it doesn't, you're good to go.
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