I bet you could - but with some reasonable precautions it can be avoided. We like Honey Dust - which is straight powdered sugar. I apply it sparingly and always to her clean vulva - not on her inner labia near her vagina or urethra.
It's fun to do a thorough job of 'cleaning her up' before moving on.
However if my partner was prone to yeast infections or UTIs, I'd probably forgo both Honey Dust and chocolate.