I love the Simpsons, but Archer is one I keep up with. South Park is hit or miss. Sometimes they are a little out there, but the movie is one of my favorites. Animaniacs still makes me laugh, and now I get far more of the humor and movie references.
There are a few anime titles I remember from my highschool days, like Cowboy Bebop, Gundam Wing, and Trigun. Haven't seen them in years and years, but I remember loving them.
As a kid, I loved loved loved Muppet Babies. There were also a few 90's nickelodeon cartoons I adored.