I use a spray-on toy cleaner on a regular basis, and while yes, you can spray on and wipe off, I often will clean it again later with soap and water, or spray and rinse. I live in a dorm, so I can't always run down the hall with an armload of toys... if you don't have instant access to a sink, a toy cleaner spray or wipes is great to do a preliminary cleaning so you can put it away until you can discretely clean them properly.
As someone with an extremely sensitive, picky pussy, I've never had an issue with the residue left by my toy cleaners (this was only before I learned much about toy safety...) Now, though, I use toy cleaners as a quick cleanup, then re-clean later. The only exception I make is a smooth glass dildo I have (and don't share, between people or orifices). Between bleachings, I do spray and wipe, and never have a problem.
So bottom line: it's a great option if for some reason you can't clean your toys immediately, or have to pull a "toss them in the bag and run." They're also good for giving them a quick cleaning before use. But they probably shouldn't be your only cleaning method.