When I was younger, it happened a number of times. I used to drive ridiculous distances, and would almost always try to drive straight through. My friends and I took a lot of roadtrips, and I was in two long-distance relationships with my s/o several hundred miles away.
Several times, I nodded off at the wheel. Once, the guardrail woke me up, which was super scary.
Now, I'm really boring on roadtrips. Not too many hours behind the wheel, regular rest stops, and plenty of sleep.
I agree that working 40 hours straight is just ABSURD. Sounds truly horrible. I worked 16 hrs straight once and felt like a superman for surviving it. How is 40 hrs straight even possible?!