I would probably be somewhat disappointed but gifts are gifts. They are free and provided with no strings or conditions. So, although it is really nice to get feedback on gifts and especially to see someone enjoying something that I spent time on, I don't feel it is required.
There could also be other factors at work here too, depending on context like other posters suggested. I don't know if he's busy, decided to cut back on sweets, going to eat it later, or just doesn't realize that his acceptance of your cake is important to you.