it depends on if the surface is smooth or not as well as the toy's material. also, some cleaning methods for silicone involve boiling or a dishwasher. but that's for toys w/o a motor.

Depends on the material. I use nothing but silicone in order to be easy to clean.

I just use anti-bacterial soap. THis is completely sufficient for zero porosity metal and glass. Silicone, which may have slight surface pores, should be fine this way, but if you are paranoid, boil it for a few minutes. I don't think other materials make good anal toys, so assuming what you have is one of these materials.